Socio-spatial differentiation has been identified not only in capitalist market economies but also in transitional countries, including post-reform China. However, most prior studies on this topic in Chinese cities are limited to a spatial resolution of the sub-district level, and finer scale analyses remain scarce. Drawing on this gap, this article provides a block-level examination of the socio-spatial changes in the central city of Beijing by employing the Beijing Travel Survey data, which contain rich socio-economic information. Latent class analysis and GIS visualisation are used to stratify the residents into different levels of socio-economic well-being based on multiple attributes and analyse their spatial distribution. The findings reveal a dramatic transformation of the socio-spatial landscape in Beijing in only five years between 2005 and 2010; 90% blocks show a greater than 10% increase or decrease in the average social stratification index of their resi- dents. The socio-spatial changes can to a large extent be related to the market reform of China’s economy and housing distribution, which exerts its influence through not only commercial devel- opments but also profound interactions with the public sector.